Personal skincare consultation | Free delivery for orders over 70 eur

Biotrade anti-age serum with retinol 0.5% 30 ml

Biotrade anti-age serum with retinol 0.5%

30 ml

Personal skincare consultation
Free delivery for orders over 70 eur

Serum with retinol against wrinkles and imperfections

Suitable for enhancing the results achieved by products with a lower concentration of retinol.

Introducing a new generation retinol face serum designed to smooth fine lines and wrinkles, stimulate collagen synthesis, and activate skin regeneration. This serum addresses the signs of aging by increasing skin density, firmness, and elasticity, imparting a youthful freshness and radiant appearance. Furthermore, it diminishes imperfections and enhances skin texture, making it particularly effective for reducing hyperpigmentation and acne scars.

Containing a new 4th generation retinoid – hydroxypinacolone retinoate (HPR) – renowned for its superior efficiency and rapid action compared to standard retinols. HPR is activated directly within the skin, bypassing the need for additional metabolic steps. Gentle on the skin, it does not cause irritation or redness, making it seamlessly integrable into your daily anti-aging regimen without any adaptation period. Additionally, it boasts exceptional stability, maintaining its efficacy even after opening, ensuring long-lasting effectiveness.

*39% reduction in fine lines and wrinkles
*44% reduction in pigmentation
*100% tolerance with no reported side effects
*Results based on a clinical study conducted with 30 volunteers over 28 days, using HPR 0.2%.


  • Stimulates collagen and elastin synthesis
  • Reduces fine lines and wrinkles
  • Accelerates cellular metabolism
  • Promotes skin regeneration
  • Tightens, smoothens, and thickens the skin
  • Improves texture
  • Restores youthful and radiant skin appearance

How to use

  • Apply in the evening to clean and dry skin, avoiding the eye area.


  • This product is not suitable for use during pregnancy and breastfeeding.
  • It is mandatory to use SPF 50+ sunscreen during the day.
  • Avoid simultaneous use with other products containing retinol.
  • Do not combine with vitamin C, AHA, BHA, or other acids at the same time.


aqua, propylene glycol, caprylic/capric tryglyceride, tocopheryl acetate, phenoxyethanol, hydroxypinacolone retinoate, polyacrylate-13, polyisobutene, ethylhexylglycerin, polysorbate 20

Active Ingredients

Hydroxypinacolone retinoate – HPR 0.5%

An advanced and proven effective form of vitamin A, synthesized from retinoic acid and a small molecule pinacol. Retinoids (Retinol, Retinaldehyde, Retinyl esters) undergo several metabolic transformations upon application, entering our skin until they reach their biologically active form – retinoic acid. Regardless of the retinoid applied, it must be converted to retinoic acid to be absorbed by the skin. HPR is an all-trans direct retinoic acid ester and therefore bypasses the conversion steps required by other retinoids. This ingredient immediately activates its action, making it more effective and less aggressive to the skin.

Main advantages of HPR:

  • Highly effective – provides fast results as it acts directly, without the need to metabolize into retinoic acid.
  • Gentle and tolerant – does not cause irritation, redness, or sensitivity, making it suitable for all skin types.
  • Stable – HPR maintains its concentration after opening and remains effective for a long time.
  • Photosensitivity – Research indicates that HPR makes the skin much less sensitive to sunlight than standard retinoids. However, sun protection remains mandatory during use.
  • No adaptation period – unlike standard retinoids, HPR does not irritate the skin and can be introduced into the routine without the need for additional adaptation time.
  • Safety Profile – While no cosmetic ingredient is entirely risk-free, HPR has an excellent safety profile, generally well tolerated with a lower likelihood of severe side effects, making it an attractive option for those seeking retinoid benefits without associated risks.
  • Innovation – HPR represents a breakthrough in skincare science, with its unique chemical structure and mechanism of action showcasing advancements in retinoid research and development, offering promising possibilities for the future of skincare.

Free from

Free from
Free from
Free from
Cruelty Free



You can write your review here

Add a review

There are no reviews yet.

Be the first to review “Biotrade anti-age serum with retinol 0.5%”

Your email address will not be published. Required fields are marked *

Welcome back,

log in to your account


create your new account

Your personal data will be used to support your experience throughout this website, to manage access to your account, and for other purposes described in our privacy policy.

I Forgot my Password

Lost your password? Please enter your username or email address. You will receive a link to create a new password via email.

Your bag is empty

Continue shopping